Firming and hydrating
The two things it is licensed to do, and the two things the formula is arranged around: a heavy hyaluronic acid for water, and a botanical complex led by escin for the look of firmness.

GENOSYS
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Professional ampoule · Ten sealed vials
The hyaluronic acid most serums cannot use.
Heavier hyaluronic acid holds more water. It also cannot get through skin on its own, which is why ordinary serums settle for the small kind. HES runs it at 1.65 million Dalton — just under the grade used in dermal fillers — and pairs it with a roller, so the weight becomes the advantage instead of the obstacle. A full 1% of it, niacinamide at 2%, and a six-botanical firming complex underneath. Ten sealed glass vials, one per treatment.
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1.65M
Dalton hyaluronic acid, where an ordinary serum runs under a million
1%
Sodium hyaluronate, the largest active in the vial
12%
Glycerin and betaine beneath it, giving the water somewhere to stay
10 × 2 ml
Sealed glass vials, opened one at a time
What HES is
HES is HA Volume Enhancing Solution, and Korea registers it for two things: firming and hydrating. Everything interesting about it comes down to one decision — which grade of hyaluronic acid to put in the vial — and GENOSYS made the harder choice, then built the delivery to match it.
The two things it is licensed to do, and the two things the formula is arranged around: a heavy hyaluronic acid for water, and a botanical complex led by escin for the look of firmness.
The bigger the molecule, the more water it binds. At 1.65 million Dalton this one sits just below dermal-filler grade and well above the sub-million hyaluronic acid in a normal serum.
A molecule that big does not cross the surface unaided. So GENOSYS solved the delivery instead: heavy hyaluronic acid sitting on top, the same molecule carried in with a roller, then skin that fills out from underneath.
Cleanse, open, apply, absorb. It is a leave-on, not a rinse-off, and at 1% hyaluronic acid with 2% niacinamide behind it there is plenty happening on the surface.

Why the weight matters
Hyaluronic acid is the most water-binding polymer we know of, and the bigger the molecule the more water it holds. The catch is delivery: a big molecule cannot get through skin by itself, so conventional cosmetics use the small kind and accept the smaller result. GENOSYS took the big kind and solved the delivery instead.
In a dermal filler
Above 2 million Dalton
Injected
Instant plumping, placed under the skin with a needle by a clinician.
In GENOSYS HES
1.65 million Dalton
Rolled in
Intensive hydrating and firming, carried past the surface by the GENOSYS roller rather than injected.
In an ordinary serum
Under 1 million Dalton
Absorbed
Moisturising, as far as a small molecule gets on its own — and it holds less water.
This is the ladder GENOSYS publishes for its own range, and HES is the one ampoule of the six built around it. Under a practitioner’s roller that heavy hyaluronic acid is the entire point. Used on its own it is still a 1% hyaluronic acid treatment over a 12% humectant base, which is more than most serums put in.
The formula
No proprietary blend, no undisclosed complex. Here is the whole thing by weight, in two groups, each on its own scale so every active stays readable beside the base.
The base · scaled against glycerin at 10%
Glycerin and betaine are twelve percent of the vial between them. That is what keeps a full 2 ml comfortable on skin that has just been worked on, and it gives the water the hyaluronic acid draws in somewhere to stay.
The actives · scaled against niacinamide at 2%
Niacinamide at 2% and hyaluronic acid at 1% are both working doses rather than a sprinkle for the ingredient list. The phytosphingosine arrives inside a lecithin liposome, so it is carried rather than simply stirred in, and escin, butcher’s broom and centella are three of the six botanicals BIOPHYTEX brings.
sh-Polypeptide-7, copper tripeptide-1, palmitoyl oligopeptide and palmitoyl tetrapeptide-7, one part per million each — the last two together are MATRIXYL 3000, one of the most widely used peptide pairs in cosmetics. The scent is six essential oils at 0.06% between them: lavender, sweet orange, sage, sandalwood, pine and lemongrass. That is a real scent from real oils rather than a synthetic one, and it is little enough that no single fragrance allergen reaches a declarable level.

What is not in it
A professional ampoule goes on skin a roller has just opened, so what has been left out matters as much as what went in. Most brands say “free from” and leave you guessing. These five are named.
The solution is a pale brown liquid, and that colour is the botanicals’ own — there is no colourant in the formula to give it. The scent is six essential oils. With no ethanol in it there is nothing to sting freshly rolled skin.
The range
The Power Solutions are a set, and each one is chosen for the skin in front of you. Same format, same price, same 2 ml sealed vial — a different job in each one. HES is the one for skin that has gone flat and thirsty.
All six are 2 ml × 10 vials at the same price, so the choice is about the skin, not the budget.
How to use it
One 2 ml vial per treatment. Ten to a box.
Wash the face and pat it dry.
Break the seal on one vial. Each 2 ml vial is a single dose.
Pat the solution over the face.
Let it sink in. This one stays on — it is not rinsed off.
Under a practitioner, a roller carries the heavy hyaluronic acid past the surface instead of leaving it sitting on top. That is the treatment this vial was built for. Follow the protocol you were given.
Throw away whatever is left in an opened vial rather than keeping it.
Dermatologically tested, and made for professional treatment or for home use on a practitioner’s advice. For external use only. Keep it away from the eyes, and rinse with cool water if it gets there. The scent is botanical oils, so patch test first if those are something you react to.
What is doing the work
Every figure below is the finished concentration in the vial, not the dose of a premix. Where a named complex delivers several of them, it is credited once and its parts are listed.
At 1.65 million Dalton this is heavier than the hyaluronic acid in an ordinary serum, so it binds more water — and at 1% it is the largest active in the vial. The reason the product exists.
Vitamin B3 at a concentration that does something. Only glycerin outweighs it among the ingredients here doing visible work on the surface.
The humectant floor under the hyaluronic acid. Twelve percent of the vial between them, and the reason a full 2 ml feels cushioning rather than tight.
Six botanicals in one complex: escin from horse chestnut, butcher’s broom root, ammonium glycyrrhizate from licorice, centella asiatica, calendula and hydrolysed yeast protein. Rich in saponins and flavonoids, and the firming half of the formula.
Palmitoyl oligopeptide and palmitoyl tetrapeptide-7 together, one of the best-known peptide pairs in cosmetics, at one part per million each.
The peptide that marks the Power Solution range. A single-chain recombinant human peptide grown by fermentation from a synthesised copy of the somatotropin gene, so it is the same 217-amino-acid sequence every time instead of varying the way a plant extract does. Listed as a skin protectant.
A copper-bound tripeptide, long established in professional skincare and dosed in parts per million, where it is classed as a skin conditioning agent.
Exactly the concentration Korean formulators reach for when a product is about the look of firmness.
A ceramide precursor, delivered in a lecithin liposome alongside lactic acid so it is carried rather than mixed in. It supports the barrier that keeps the water on the inside.
Pro-vitamin B5, at a real dose. It is what leaves the surface comfortable on the evening of a professional session.
Aqua (Water), Glycerin, Butylene Glycol, 1,2-Hexanediol, Niacinamide, Betaine, Sodium Hyaluronate, Panthenol, Phytosphingosine, Lecithin, Escin, Ruscus Aculeatus Root Extract, Adenosine, Ammonium Glycyrrhizate, Centella Asiatica Extract, Hydrolyzed Yeast Protein, Lavandula Angustifolia (Lavender) Oil, Citrus Aurantium Dulcis (Orange) Oil, Salvia Officinalis (Sage) Oil, Santalum Austrocaledonicum Wood Oil, Pinus Sylvestris Oil, Cymbopogon Schoenanthus Oil, Lactic Acid, Calendula Officinalis Flower Extract, sh-Polypeptide-7, Copper Tripeptide-1, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7, Sodium Chloride, Sodium Phosphate, Carbomer, Polysorbate 20, Disodium EDTA.
Every ingredient, in the same order as the box in your hand. Ingredient lists stay in Latin script in every language, because that is the form regulators require.
Is this the right vial
All six are the same format at the same price, so there is nothing to gain from buying the wrong one. Ask your practitioner which of the six your skin is actually asking for.
Specification
Questions
No, but it is what the heavy hyaluronic acid was chosen for. Cleanse, open, apply, absorb, and used that way it is a 1% hyaluronic acid leave-on over a 12% humectant base with niacinamide at 2% — a strong treatment by any standard. With a roller, in a practitioner’s hands, the molecule gets past the surface instead of holding water on it, and that is the difference the product was built for.
Because of the plants in it. Escin, butcher’s broom, licorice, centella and calendula all carry their own colour, and there is no colourant in the formula to standardise it away. A pale brown liquid is the specification, not a fault.
Yes, on your practitioner’s advice, and it is worth asking rather than guessing — they will know whether your skin wants HES or one of the other five. Applied by hand it needs nothing but clean skin. Do not use a roller on yourself without being shown how.
There is no ethanol in it, which is the usual culprit on freshly treated skin, and the pH sits near neutral at 5.75. The scent is six essential oils rather than synthetic perfume, so if botanical oils are something you react to, patch test first.
Two things: the weight of the molecule and the amount of it. A pharmacy serum almost always uses hyaluronic acid below one million Dalton, because that is the grade that absorbs unaided, and rarely at 1%. This is 1.65 million Dalton at a full 1%, in a sealed single-dose vial so it is as fresh as the day it was filled.
Ten treatments, one vial each. In a clinic that is a course; at home, spaced the way your practitioner tells you to. Unopened the box keeps three years, and the expiry date is printed on it.

Ten treatments, sealed one at a time.
POWER SOLUTION HES
Hyaluronic acid at 1.65 million Dalton, a full 1% of it, and every other percentage listed above, nothing held back.